Online Evidence-Based Databases

The American Physical Therapy Association (APTA) recognizes that physical therapists must be able to easily access clinical research if they are to practice evidence-based physical therapy as they provide clinical services. Given the importance of evidence-based practice to the achievement of the APTA’s Vision Statement for Physical Therapy 2020, the Association has developed Open Door: APTA’s portal to evidence-based practice. Open Door will provide members with easy access to journals and other resources relevant to clinical practice whenever and wherever they need it.

This database of summaries of articles from the major medical journals, together with expert commentaries, is the CD-ROM equivalent of the combined ACP Journal Club and Evidence Based Medicine output. Details of subscriptions are found at the BMJ site. 

Clinical Evidence is a database of clinical questions designed to help clinicians make evidence-based medicine part of their everyday practice. Hundreds of clinical questions cover the effects of treatments and interventions based on the best available research. Topics are selected to cover common or important clinical conditions seen in primary care or ambulatory settings. Questions are selected for their relevance to clinical practice by leading physicians in conjunction with other practicing physicians and patient groups. Answers are the result of thorough research commissioned by the prestigious BMJ Publishing Group (British Medical Journal), employing premier medical resources including the Cochrane Library, MEDLINE, EMBASE, ACP Journal Club. Rigorous peer-review of all material by independent experts, an advisory board, and an international advisory committee aims to ensure that the information is of the highest quality.

The U.S. National Institutes of Health, through its National Library of Medicine, has developed ClinicalTrials.gov to provide patients, family members and members of the public current information about clinical research studies.

A rapidly growing collection of regularly updated, systematic reviews of the effects of health care, maintained by contributors to the Cochrane Collaboration. New reviews are added with each issue of The Cochrane Library. Cochrane reviews are reviews mainly of randomized controlled trials. Evidence is included or excluded on the basis of explicit quality criteria to minimize bias. Data are often combined statistically, with meta-analysis, to increase the power of the findings of numerous studies each too small to produce reliable results individually. Although the Cochrane Database of Systematic Reviews is available on subscription only, the Abstracts of Cochrane Reviews are available without charge and can be browsed or searched.

A rapidly growing collection of regularly updated, systematic reviews of the effects of health care, maintained by contributors to the Cochrane Collaboration. New reviews are added with each issue of The Cochrane Library. Cochrane reviews are reviews mainly of randomized controlled trials. Evidence is included or excluded on the basis of explicit quality criteria to minimize bias. Data are often combined statistically, with meta-analysis, to increase the power of the findings of numerous studies each too small to produce reliable results individually. Although the Cochrane Database of Systematic Reviews is available on subscription only, the Abstracts of Cochrane Reviews are available without charge and can be browsed or searched.

This facility from Update Software allows you to search the abstracts of the Cochrane Database of Systematic Reviews. The full-text of the reviews is only available through the Cochrane Library above.

DARE is a database of high quality systematic research reviews of the effectiveness of health care interventions produced by the NHS Centre for Reviews and Dissemination at the University of York.

A list of the latest articles on Evidence Based Health Care provided by the Evidence Based resource Centre in New York.

Evidence Based Medicine Reviews (EBMR) is an electronic information resource. Available both via Ovid Online and on CD-ROM, this database from Ovid combines three EBM sources into a single, fully-searchable database with links to MEDLINE® and Ovid full text journals. Sources covered include:

1. The Cochrane Collaboration’s Cochrane Database of Systematic Reviews
2. Best Evidence, which consists of ACP Journal Club and Evidence-Based Medicine from the American College of Physicians and the BMJ Publishing Group.
3. The Database of Abstracts of Reviews of Effectiveness, produced by the expert reviewers and information staff of the National Health Service’s Centre for Reviews and Dissemination (NHS CRD. 

Guideline is a UK-based initiative to develop an electronic database of critically-appraised, clinical practice guidelines for healthand allied care professionals across the National Health Service (NHS). The project began in March 1997 and is funded by the four health authorities of Oxfordshire, Berkshire, Buckinghamshire and Northamptonshire until August 1998.

Reports and issue briefs from the HTAC in Minnesota.

The HTA Database, mounted by the NHS Centre for Reviews and Dissemination at the
University of York, contains abstracts produced by INAHTA (International Network of Agencies for Health Technology Assessment) and other healthcare technology agencies.

Searchable database of POEMS (Patient Oriented Evidence that Matters) from the Journal of Family Practice. POEMS are summaries similar to ACP Journal Club articles in methodology and format, targeted at family practitioners.

Medical SmartSearch is a single gateway that attempts to provide references to answer clinical questions around diagnosis, etiology, prognosis and therapy (plus physical findings, adverse treatment effects and screening/prevention) by searching only high-quality sources.
Smartsearch always searches:

1. Merck Manual.
2. MEDLINE for review articles and editorials that have full texts available.
3. National Guideline Clearinghouse from the Agency for Health Care Policy and Research
4. Database of Abstract of Reviews of Effectiveness (DARE)
5. MEDLINE for original research.
Depending of the focus requested SmartSearch will search PubMed with the highest
sensitivity filters developed by Haynes et al.

This WWW resource contains the following collections: AHCPR Supported Guidelines, AHCPR Technology Assessments and Reviews, ATIS (HIV/AIDS Technical Information), NIH Warren G. Magnuson Clinical Research Studies, NIH Consensus Development Program, PHS Guide to Clinical Preventive Services (1989) and SAMHSA/CSAT Treatment Improvement Protocol (TIP).

The National Research Register (NRR) is a register of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom’s National Health Service. The current release contains information on over 57,000 research projects, as well as entries from the Medical Research Council’s Clinical Trials Register, and details on reviews in progress collected by the NHS Centre for Reviews and Dissemination.

The NHS Economic Evaluation Database is a database of structured abstracts of economic evaluations of health care interventions produced by the NHS Centre for Reviews and Dissemination at the University of York.

PEDro, an initiative of the Centre for Evidence-Based Physiotherapy (CEBP). PEDro is the Physiotherapy Evidence Database. It has been developed to give physiotherapists and others rapid access to bibliographic details and abstracts of randomised controlled trials in physiotherapy. Most trials on the database have been rated for quality to help to quickly discriminate between trials which are likely to be valid and interpretable and those which are not.

This site will include all guidelines, evidence-based, consensus, practice parameters, protocols, as well as other resources such as primary articles, integrative studies, meta-analysis, critically appraised topics, and review articles. Compiled by Peter Sam at the UCSF School of Medicine.

RehabTrials.org is a new web site created by the non-profit Kessler Medical Rehabilitation Research and Education Corporation (KMRREC) to promote, encourage, and support clinical trials in medical rehabilitation.

SUMSearch is a single gateway that attempts to provide references to answer clinical questions around diagnosis, aetiology, prognosis and therapy (plus physical findings, adverse treatment effects and screening/prevention) by searching only high-quality sources. SUMSearch always searches:

1. Merck Manual.
2. MEDLINE for review articles and editorials that have full texts available.
3. National Guideline Clearinghouse from the Agency for Health Care Policy and Research (AHCPR)
4. Database of Abstract of Reviews of Effectiveness (DARE)
5. MEDLINE for original research. Depending of the focus requested SUMSearch will
search PubMed with the highest sensitivity filters developed by Haynes et al.

This resource, hosted by the Centre for Research Support in Wales, aims to support those working in primary care. The database has 8000 links covering resources at 28 different centres and allows both boolean searching (AND, OR, NOT) and truncation.